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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '22564d8af1712066f048fd6d09c6bef8e9275e774ee8633f74fa88ccedb63697' 
  AND token = 'zbRKInaImllF368UZzSa8AxYRI0MWSlJikvHcWCuQHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}