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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8b099a828d9eae979d54fcc8a028fc86928fc85e658f3adf374f0eb02547f577' 
  AND token = 'CYxtOFIXAqkc7rQvU2NtapZW9jhsX/CL1fde3QGY1mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}