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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4fd25f1cf140cc8da1de29de2af41d1cc9206112f1a24d706fa99d51438a0f6f' 
  AND token = '9wp4Gy1Z7TK9N/zjoSAslUDOOaoc+dz+wkfbjNr5nik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}