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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2f0b2c46fa5910f09b856546252a083e4972c96c8ab90229ed1d11918164d47d' 
  AND token = 'VMCEeQ2SE1tyhm3Qeh/CKgBMNnChoWpmqDo27O5xxQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}