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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2a5fce02c86089047a006e2b8490ad75996d1c95f7ff9474cefee263736bfde4' 
  AND token = '/IvWwzpzPwr6cOI845/2QTj7r8RoGXytcXlOkwSgsxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}