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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '53f38093b0416aa5584c0a73a1355fc57bb858100838b068a0f26eb3356f0c4f' 
  AND token = '6dEjtBHTm4mruU/xLr/vdRFdA49ylJyj/nXB781AYJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}