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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '10b9eff3e01d53faede288d1caa69cfd6dcea9a1be16a277e385237203fee8a8' 
  AND token = 'Vtey50TMXHJycT8n+tMFGeQUy0AKGXOKuWh9v3+rFrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}