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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '141ab5583cdae255da7a73234cd00dd509eb57f6e3c6df5ed4af01ccdc074404' 
  AND token = 'QtAufHQNCMSyeouTP9Z6BZSKDxF9zatuklfzsI8rz94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}