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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1fc54c09eaa16cbb587a5188f3a76e42a302e18e8b9e54ecb6011b80a26271a7' 
  AND token = '+NjVC38gTJI7GoC/WAoSDd1DEl5Wuxs5kSM5xSXSyyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}