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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '867687f7f7e7dcdad0c0558f15b226a3086fcc70a2d1729d36b275885a898fc2' 
  AND token = 'likezemtI5/4G3hoVELjsOkN7EHkBQ1eTb2MoPGy6eM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}