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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '526c5567c4b8e285da137c178a3ff8e609bb217880a932c99cab7ce500968605' 
  AND token = 'M2C+ZE3MHbaSFMnb8Gg9flOddCWpGKIagXcXKbTmFcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}