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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5eb77bbef21535bdb848a5362df13151f9e3acaa03c8053e603633563278341b' 
  AND token = 'L+Ro6YuTECMQYdhsqkF/oew3bTyYrYAWYtcUAfPFoCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}