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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '42749760fd8838963865471f6b67912ed5210d252c98b726cce65f6196790df0' 
  AND token = 'MtcRh7Bh7nkWdHIxggAF8tl6isbc7eOIEvbac81CMcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}