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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4a18a7e426ff2fd825b6fe2829675efe090de347c8309d0d81855c144f5692ca' 
  AND token = 'MoFLUoD7fSd87duupD69uZ9D/MC7U4T16t4k8IyZQUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}