Sandbox

SELECT 
  1 
FROM 
  cscart_june_setupec_print_temp_designs 
WHERE 
  session_id = '64UG-XL5A-58F4-G0Y7-7EHQ-T7K3-HYS1-FUXY' 
  AND product_id = 42 
  AND expires_at > 1781886139 
  AND confirmed = 'Y' 
LIMIT 
  1

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}