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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '3b9a5f4c5fb6425d85c679a9b24466572095a615b751c56556ad871250e8d181' 
  AND token = 'ztbqpi6MwAAQeNIMtHYhEUYlabe5zcwL+b+9jcQuTtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}