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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b36afa21b14823ccc90b39bc927e3bb71fdd6c536cfc74afb22e9be8b686371d' 
  AND token = 'cruYkkuxGrmcpbF++PS2iqp2ZTrOJan/FBBM7Mw+j/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}