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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ed81d9b28642a000590994dfed682e78157f1c5a5b8563b837fee5c55e034207' 
  AND token = 'C2MKca8vcg2tNSNFQOTTy54aMIslGkThga2IQmA8tz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}