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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '3b43abd0cc3a7077268639f61d2a617b4e349f05feb1fc9d93686e09fb083dc3' 
  AND token = 'KP5LaO7E7SsTtlT6MP4yvc2IZ2lT71JxsBUapj33YrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}