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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a8e6fb6c7d5d2610b3aa84bf4e108c6f2b15dece2255bbb07248a2b90a4b8664' 
  AND token = '+U4n+BSUFaHt20EMDtPRsaWybT+G+6yAmsPG10/T5T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}