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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4879bd6bb6abf65a326c772b4af06b2567e989dd580b3b94be8088fe6fb6c038' 
  AND token = 'F70H+b4ZL/sSO6eDpgVb8y07qaCoS15Eh7wZnzVkIgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}