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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '812fdc9509ea508f6ba03df15a63e19122b267749b4ed8021d5382a587e119b7' 
  AND token = 'rYT+bfFpdD9lxNn3LMRrWqOFyVP7m8EgDeKjVTbOg0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}