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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'aec5283a271504d250b098061cda0635774c4fc037c8f081a690cbf05d2b7095' 
  AND token = '6ebrL0rrtW+fXRQSTGFa/U3cjpHfeH8AiyF/loIw6R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}