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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7b39241b41c4d112020a4c4204f166d7a761b8a0b7fdd514a46a29d85efdc191' 
  AND token = 'dn2F1XQHnZvbSHX8sOGToS7B1+lFpWgJOAd9Ec/EO7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}