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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c05286015df40d484ab07cecc9a9d68bc90ec917046f2128dc940cd4f16805ed' 
  AND token = 'o8SFnT+4QUyOIgTja5uF1LwHEMwG8uuCJossV38ySNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}