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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd54e8c7a497a713585a404e8f4db4b739d8cef39243855de2b12a18ae921f577' 
  AND token = '+UCO1SAYt0BNQpQWh6qZuN1ALjqlbASOEqrFXMc9ce0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}