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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '561753544bde9657ca08d3ceb514ed5ce6b2b65f149cb0207a759b86b908b80b' 
  AND token = 'a03IsgTTZdsVq1kwG9Hwc+uSfbKPntwc9V8Yg2TyNL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}