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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4c17a397c548f0b1ad36786bd301be9dc4aa692fda501ec8c858a7d51351a01b' 
  AND token = 'p4uUVnZSBwUN+ud1X7TT7DPIoQzMlaeRzIQuU72ukH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}