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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd5db37428d1c9553115a712c35bedaa3a786c474f74e486d04167106ae74cab2' 
  AND token = 'h/Z6ey0wKbZQwtTJJYcd1dO1UJCdleiMyD9SAnm4Yn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}