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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8b476da055c73f59e19cee3a408154681608ca22deaad9324b24bb411f3a7924' 
  AND token = 'MD0KxyAIrClw3WycZwNSCmEEkPPQaAMJgtVhPZ9eWuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}