SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '17aeb7f51b110e8a397dc97b803d55ad431aad5a3f308fe6bd572e0081de828f' 
  AND token = 'slLhKqjVBZE0aGnnUWgcILnPePn2xtEHnbiXxh03j4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}