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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '78557142f285b6ca3a564af996fe014dde7a2344c7817bf67da5a2ad13316c9c' 
  AND token = 'EZaE5QUe6Eocq7m55PmQ94TSYa/d72cCu1kt5orcgsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}