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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0438897674bb58b76a651dcd0483fb2d6a57fbed9d5b9b817a9906f01b32db35' 
  AND token = '3U89VMoqcw6S/niqlHmcaTdE7Dw66UWmQejSytE1gwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}