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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2b2301a28d8b37d3ac2c6be6e5d5024d80ca53cdd54bc1ee4ecbe6fa1074dfcd' 
  AND token = 'Vv5hK17+bcaf7KYtV8pWEjvXBI8wuycU1vCiif606Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}