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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '305963d0238114bd522e4f1e763504fff961021c699840f52725aa55d25eaf67' 
  AND token = 'GpG8l9EeM3Ns1mHxMJP7CsKefZY4MMZftItnnQaeSt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}