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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8621e66bcc4d0f29306782ee63f776fae16ea74fe2b1c11947a89e572c4a562b' 
  AND token = '+nO5AbcNrXYHldIgTJycpLC/qRiCQuHYAVgoblaO+lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}