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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '749b3b4446b02d1cb3280aeb6827e08b1f7026640e34db2ea812f99f9253dbea' 
  AND token = 'caOMXCZhKzv5C9u1AiQuPk9qI2PDNLRZDNkXw3bQ5mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}