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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '01c00afc441030c5f96a3286c3de6263f29f9c8cb09afffdf8efe36631c785bb' 
  AND token = 'jbp3pj1c8NGJA1daLaaFQfKDlXKCqxHXuVNxB56RPx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}