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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2b336ba77317fdcd82d8928ef071447359bcef3aba1c4fdda2c1074711a18f24' 
  AND token = 'XN/NJolle0Aiioxa/UPPkvR1Igy196lMVPnN1P2oIFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}