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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '48f041cd99ff203ad20e1732f0f78eb73188fcc02767d8294a16be370a8fbd4f' 
  AND token = 'wK5wW+aiQS/nJMKRievsyxho+4F7737IcXI1a7Kq3cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}