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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '922bc3f3829c387f917ec5efad140e6fbf0cfa88971586a9d7a0ca0085e5de86' 
  AND token = 'M4Exjn+3V/OShGSnOPRnrEX9OUq0QTeS6CRP9p9xV/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}