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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '24dd254562ab753f8cad52e8189ddd61e57721b5c60d5b17969534aa5df3136c' 
  AND token = 'Zmp37QRPQMisfC41XRsHnWl8k/AiG6HS3ijI0fBs2Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}