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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '70a1a03097eec5a1ad02f2f200576bd7cad83de0e3411bed1fa99a652265ed18' 
  AND token = 'LFPyzFnIICgpC2o+N2kertz5IMaR1eMEwt1vp6IOjvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}