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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e22c6704d15d1c604ee88b2b39ed9bff585e99e1692275933b2f5ade0f6854c0' 
  AND token = 'bwbItiIxntXisckENk0gQ01eEl//aq8axc61VMjsB2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}