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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1ed57a29759cb405a914aeabd460e31ba9e23b960959ea19cc32d409fe768767' 
  AND token = 'es1l9ECs07QhWOrt9eJs505kiy+o2yBOB5xfTYbFRt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}