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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '16acbcbad6ecd4b1db53fdcdce7e587fdf42b2ca1bdc0606e477bab534d610f0' 
  AND token = '8130W7W4uhqLBJDFfCdWnzdB+cTVkWFicNqT8ZwEZCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}