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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8e429b296e8162d70aa37744b27cd6e77df67649786c99f0486e1f1a6390b294' 
  AND token = 'rwyvU2v2YudArHVTsE7MwigG00fIDCYjkLlslPYkbbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}