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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '643133df0edbbb089555ab7fa1547cb5ac3af7d45d2bdba92923a820b2734f79' 
  AND token = 'kwQY/MhrF26m0jSQ1y1eCK8ikdd/dFrhTQj/rZWazpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}