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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'af0c441cd3c606946b8ae39e87437f3e5322030888bea91464af4e5c325508d3' 
  AND token = 'VS2F4daLvUoduYEE8ZJ4i8yamEmQtduDhdj30PfiK4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}