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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c3d91e6c60190655d78c703f620afb551a31eb7fda9830b7245dd9486946d9ef' 
  AND token = 'TLpcjZkabeM2XSHQXHZp5838HjFTUkUfAdure25AoII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}